The PROTEUS Trial: Perioperative Apalutamide Shows Positive Results for Prostate Cancer

The PROTEUS phase 3 trial, published in the New England Journal of Medicine, shows that adding perioperative apalutamide to androgen-deprivation therapy significantly improves outcomes for men with high-risk localized or locally advanced prostate cancer undergoing radical prostatectomy. The international trial randomized 2,109 patients to six cycles of ADT plus apalutamide (240 mg daily) or ADT […]

Final OS Data from EMBARK Phase 3 Trial: Enzalutamide With ADT for Men at Risk of BRPC

Data from the phase 3 EMBARK trial, combining enzalutamide with standard hormone therapy, recently published in The New England Journal of Medicine and presented at the 2025 European Society for Medical Oncology (ESMO) Congress, reveal that this combination reduces the risk of death by more than 40% over eight years compared to hormone therapy alone. […]

Positive Results From Phase 3 Trial of CAN-2409 for Localized Prostate Cancer Led to RMAT Designation