CRISPR: Gene Breakthrough Could Starve Cancer Cells of Vitamin D
/in CRISPR, Preclinical Research/by MaxBreakthrough in Cancer Immunotherapy: In Situ CAR-T Cell Generation Offers Hope for Lymphoma and Beyond
/in Immunotherapy, mRNA, Preclinical Research/by MaxA groundbreaking study led by Stanford Medicine, published in Cancer Immunology Research, has introduced a revolutionary approach to generating chimeric antigen receptor (CAR)-T cells directly inside the body, offering a promising new avenue for cancer treatment. This “in situ” method, which uses mRNA delivered via lipid nanoparticles (LNPs), successfully treated B-cell lymphoma in mice and […]
Korean Team Unveils Breakthrough All-in-One Cancer Nanomedicine
/in Preclinical Research/by MaxIn a groundbreaking advancement for cancer treatment, a team from the Korea Research Institute of Standards and Science (KRISS) has developed an innovative nanomaterial that could transform cancer care. This “all-in-one” nanomedicine, known as gold-iron-gold nanodisks (AuFeAuNDs), integrates diagnosis, treatment, and immune activation into a single platform. Still in pre-clinical stages, this discovery shows significant […]
MDNA113 a Potentially Groundbreaking Immune Therapy for Solid Tumors Including mCRPC
/in Immunotherapy, Preclinical Research/by MaxDiWB-1: A Targeted Approach to Prostate Cancer Treatment
/in Pepetide-Drug Conjugate, Preclinical Research/by MaxDiWB-1, a luteinizing hormone-releasing hormone (LHRH)-targeted peptide-drug conjugate (PDC) with PI3K inhibition properties, is an emerging candidate that may offer a new way to treat prostate cancer. Its design and mechanism suggest potential for addressing some of the limitations of current treatments, particularly for resistant cases. DiWB-1 is described as an LHRH-targeted PDC, a class […]
New Method Uses Nanoparticles to Create CAR T Cells Inside Body for Cancer Treatment
/in mRNA, Preclinical Research/by MaxCholesterol Identified as Key Shield in Heat-Resistant Cancer Cells
/in Hyperthermia, Preclinical Research/by MaxAspirin: New Insights Into Its Mechanism of Interaction With Cancer
/in Drug repurposing, Preclinical Research/by MaxProject Navigator
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- GSK5764227: An Antibody-Drug Conjugate Targeting B7-H3 Enters Phase 1/2 Trial December 12, 2025
- MHB048C: A New PSMA-Targeted Therapy for Advanced Solid Tumors December 12, 2025
- Logic-gated DARPins, a Promising Advancement in Immune Therapy for Solid Tumors December 11, 2025
- CONVERT‑HB1: a Phase 2 Trial About Prostate Directed Treatment After Systemic Treatment in mHSPC December 11, 2025
