Tag Archive for: mHSPC

CONVERT‑HB1: a Phase 2 Trial About Prostate Directed Treatment After Systemic Treatment in mHSPC

CONVERT‑HB1 trial addresses a long‑standing uncertainty in metastatic hormone‑sensitive prostate cancer: whether aggressively treating the primary prostate tumor adds meaningful benefit for patients who already have high‑volume metastatic disease and are receiving modern intensified systemic therapy. For years, data from studies like STAMPEDE and HORRAD suggested that local treatment to the prostate might help men […]

European Commission Approves Darolutamide Plus ADT for Metastatic Hormone-Sensitive Prostate Cancer

The European Commission has granted marketing authorization to darolutamide (Nubeqa) combined with androgen deprivation therapy (ADT) for treating metastatic hormone-sensitive prostate cancer (mHSPC). This approval, following a positive opinion from the European Medicines Agency in June 2025, allows darolutamide plus ADT to be used with or without docetaxel, offering clinicians greater flexibility in tailoring treatment. […]

AMPLITUDE Trial Update: Niraparib Plus Abiraterone Shows Promise for HRR-Altered Metastatic Prostate Cancer

Darolutamide Plus ADT and Docetaxel Extends Survival in Metastatic Hormone-Sensitive Prostate Cancer by Disease Volume and Risk in ARASENS Trial