Healthy Eating After Prostate Cancer Tied to Lower Risk of Frailty

Eating a healthier diet after a prostate cancer diagnosis may help men age with more strength and resilience, according to a large prospective observational U.S. study that will be presented at the AACR 2026 meeting. The analysis followed more than five thousand men from the Health Professionals Follow‑up Study who were not frail when they […]

Higher Vitamin D Levels Before Diagnosis Linked to Better Prostate Cancer Survival

A large international pooled analysis of over twelve thousand men with prostate cancer adds substantial evidence that men who have higher circulating levels of vitamin D before their diagnosis tend to live longer after developing the disease. The study, which will be presented at AACR Annual Meeting 2026, focused on 25‑hydroxyvitamin D, the major blood […]

Darolutamide Linked to Better Real‑World Outcomes than Enzalutamide or Apalutamide in nmCRPC

A large real‑world study in nonmetastatic castration‑resistant prostate cancer (nmCRPC) called DEAR‑EXT, published on Nature, has added new detail to how the three androgen receptor inhibitors (darolutamide, enzalutamide, and apalutamide) behave outside of randomized trials, using data from over 1,300 men treated in US urology practices between 2019 and 2023. The analysis builds on an […]

Blood Lipid Profiles in Metastatic Prostate Cancer: A Window into Tumor Metabolism and Response to Enzalutamide

A recent study, published on Nature, in metastatic castration‑resistant prostate cancer (mCRPC) shows that a simple blood test can reveal important information about how the tumor is reprogramming its metabolism and how it responds to enzalutamide, a common androgen‑receptor‑targeting drug. Researchers analyzed the entire circulating “lipidome” (the full panel of fats and related molecules in […]

Molecular Fingerprints of Aggressive Prostate Cancer: How Spatial Multi‑Omics Could Transform Early Risk Detection

A study used prostate tissue from patients who had undergone surgery, some of whom later relapsed and some of whom remained cancer-free many years afterward. By comparing these two groups, the research team could define which samples represented aggressive disease and then search for molecular features that consistently separated them from indolent tumors. The original […]

ASCO GU 2025: Impact of Homologous Recombination Repair Alterations on Survival Outcomes in Metastatic Hormone-Sensitive Prostate Cancer (BRCA, ATM, CDK12,…)